Metabolic syndrome in reproductive age: A cross-sectional study
- سال انتشار: 1404
- محل انتشار: International Journal of Reproductive BioMedicine، دوره: 23، شماره: 5
- کد COI اختصاصی: JR_IJRM-23-5_003
- زبان مقاله: انگلیسی
- تعداد مشاهده: 13
نویسندگان
Department of Internal Diseases no. ۱, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
Department of Therapeutic and Orthopedic Dentistry, Khoja Akhmet Yassawi International University, Turkestan, the Republic of Kazakhstan.
Department of General Hygiene, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
Department of Pharmacology, Kazakhstan-Russian Medical University, Almaty, the Republic of Kazakhstan.
Department of Internal Diseases no. ۲, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
Department of Surgical and Pediatric Dentistry, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
Department of Pedagogy, International University of Applied Sciences in Lomza, Lomza, Poland.
چکیده
Background: Obesity and metabolic syndrome (MetS), as components of excess body weight, have reached global epidemic levels. Objective: The study aimed to investigate the features of the MetS course in men and women of reproductive age. Materials and Methods: This cross-sectional study was conducted with ۱۴۰ participants aged between ۳۵ and ۴۹ yr at City Polyclinics No. ۱, ۳, and ۴, Aktobe, Kazakhstan from March ۲۰۱۶-۲۰۱۹. Participants were divided into ۲ subgroups based on diagnosis of MetS. The case group (with MetS), and the control group (without MetS) (n = ۷۰/each consisted of ۴۰ women and ۳۰ men). Anthropometric, instrumental, and laboratory methods were used to confirm the diagnosis of MetS and determine its features in both groups. Results: The results showed an increase in the uric acid level in the blood to ۴۳۱.۰۰ ± ۶۶.۳۷ μmol/L and ۵.۴۷ ± ۰.۹۰ mol/day in the urine. Dyslipidemia was also noted in the case group of individuals with high-density lipoprotein levels of ۱.۲۲ ± ۰.۲۷ mmol/L vs. ۱.۳۲ ± ۰.۴۷ mmol/L in the control group. The testosterone level was ۱۶.۴ ± ۳.۰۴ nmol/L in the case group and ۲۰.۳ ± ۵.۶ nmol/L in the control. The difference in testosterone level was found to be statistically significant (p ˂ ۰.۰۱). Conclusion: The analysis of sex hormone levels did not reveal any stable trends that could be considered diagnostic. That may indicate a correlation with the reproductive age characteristics of the examined individuals (men and women): significant differences between hormone levels were fixed in the case and control groups.کلیدواژه ها
Metabolic syndrome, Abdominal obesity, Dyslipidemia, Insulin resistance, Sex hormones., سندرم متابولیک, چاقی شکمی, اختلال چربی خون, مقاومت به انسولین, هورمون های جنسی.اطلاعات بیشتر در مورد COI
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