Convenient and Robust Metal-Free Synthesis of Benzazole-۲-Ones Through the Reaction of Aniline Derivatives and Sodium Cyanate in Aqueous Medium
- سال انتشار: 1399
- محل انتشار: Iranian Journal of Chemistry and Chemical Engineering، دوره: 39، شماره: 5
- کد COI اختصاصی: JR_IJCCE-39-5_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 73
نویسندگان
Department of Chemistry, Payame Noor University, Tehran, I.R. IRAN
Department of Chemistry, Payame Noor University, Tehran, I.R. IRAN
Department of Chemistry, Payame Noor University, Tehran, I.R. IRAN
School of Engineering Science, College of Engineering, University of Tehran, Tehran, I.R. IRAN
Department of Chemistry, Payame Noor University, Tehran, I.R. IRAN
چکیده
Benzazole-۲-ones (benzimidazolones, benzothiazolones, benzoxazolones) are important derivatives of benzazole compounds that exist widely in many biologically and pharmaceutically active molecules. Furthermore, benzazole-۲-one derivatives also have many applications in agrochemical and material science. Herein, a novel, practical and green synthesis of titled compounds by the reaction of aniline derivatives with inexpensive and easily accessible sodium cyanate has been reported. Good to excellent yields of products have been obtained under catalyst- and ligand-free conditions in water as solvent. This procedure avoids the use of time-consuming and tedious column chromatography and the products were easily isolated by simple extraction followed by washing with dichloromethane.کلیدواژه ها
benzazole-۲-ones, Benzimidazolones, benzothiazolones, benzoxazolones, sodium cyanate, Green Chemistry, water, Synthesisاطلاعات بیشتر در مورد COI
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