Zinc Oxide Nanoparticles in Photodynamic Therapy: A Pathway to Enhanced Cancer Treatment

As potent photosensitizers in photodynamic therapy (PDT) for the treatment of cancer, zinc oxide nanoparticles (ZnO NPs) have attracted a lot of interest. ZnO NPs are perfect candidates for improving PDT efficacy because of their special qualities, which include excellent biocompatibility, effective reactive oxygen species (ROS) production, and specific cytotoxicity towards cancer cells. With an emphasis on their synthesis techniques, mechanisms of action in ROS production, and therapeutic results in preclinical and clinical settings, this review examines recent developments in the use of ZnO NPs in PDT. The results highlight how ZnO NPs can be used to enhance treatment outcomes while resolving existing PDT drawbacks such as hypoxic tumor microenvironments and inadequate light penetration.

کلیدواژه ها:

photodynamic therapy ، reactive oxygen species ، zinc oxide nanoparticles ، cancer treatment ، photosensitizers