Vitamin A and D Levels in Preterm Neonates: The Relationship with Morbidities and Clinical Considerations
- سال انتشار: 1404
- محل انتشار: مجله علمی ناباروری ایران، دوره: 16، شماره: 2
- کد COI اختصاصی: JR_IRJN-16-2_003
- زبان مقاله: انگلیسی
- تعداد مشاهده: 56
نویسندگان
Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Pediatric Department, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Vitamin A and D deficiency are more prevalent in preterm neonates than in term. Preterm neonates are more susceptible to various complications and morbidities, including respiratory issues, sepsis, retinopathy of prematurity, hyperbilirubinemia, anemia, and intraventricular hemorrhage. This study aims to investigate potential relationships between vitamin A and D deficiency and neonatal morbidities. Methods: Forty-four neonates, all with gestational age less than ۳۲ weeks or birth weight less than ۱۵۰۰ grams, were enrolled. Serum levels of vitamin A and D were assessed, and neonates were categorized into deficient and sufficient. Comparative analysis was conducted between groups using various statistical tests, including Chi-square test, Wilcoxon signed rank test, Kruskal-Wallis test, independent t-test, and Mann-Whitney test. Results: The mean gestational age was ۳۰.۵±۱.۷ weeks, and the mean birth weight was ۱۳۲۲.۹۵±۲۸۶.۶۷ grams. The mean vitamin A and D levels were ۲۰.۹۵±۹.۷۹ µg/dl and ۲۲.۸±۱۱.۵ ng/ml, respectively. Vitamin A deficiency was observed in ۱۹ individuals (۴۳.۲%), while ۲۹ individuals (۶۵.۹%) exhibited vitamin D deficiency. A significant association was observed between vitamin D deficiency and both duration and type of oxygen support (p-value ۰.۰۴, ۰.۰۴). However, no significant differences were found between the two groups regarding other morbidities or vitamin A status. Conclusion: Limited studies have evaluated the association of vitamin levels with neonatal morbidities. Vitamin D deficiency is common among preterm neonates and is associated with the duration and type of respiratory support. Further investigations are warranted to explore potential links between vitamin deficiencies and various neonatal morbidities.کلیدواژه ها
Bronchopulmonary dysplasia, Morbidity, Newborn, respiratory distress syndrome, vitamin A deficiency, Vitamin D deficiencyاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.