A Meta-Analysis of Antibiotic Resistance among Pediatric Populations Post-COVID-۱۹ Infection

  • سال انتشار: 1404
  • محل انتشار: مجله درمان های پیشرفته، دوره: 7، شماره: 22
  • کد COI اختصاصی: JR_PGOT-7-22_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 109
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نویسندگان

Maryam Abbasi Saeidi

Department of Biology, Faculty of Basic Sciences, Science & Research Branch, Islamic Azad University, Tehran, Iran.

Mina Ekrami Noghabi

Department of Pediatrics,Bohlool Hospital, Gonabad University of Medical Sciences, Gonabad, Iran.

چکیده

The COVID-۱۹ pandemic has exacerbated the global issue of antibiotic resistance, particularly among children recovering from the virus. A significant concern is the rise in secondary bacterial infections that occur after a viral infection like COVID-۱۹. These secondary infections often lead to the overuse or misuse of antibiotics, which has fueled the development of antibiotic resistance. Children, whose immune systems may still be developing, are particularly vulnerable to these complications, which can result in prolonged hospital stays, more intensive treatment, and, in some cases, worsened clinical outcomes.This meta-analysis explores the prevalence of antibiotic resistance in pediatric populations who have recovered from COVID-۱۹, focusing on the impact of secondary bacterial infections. Studies conducted between ۲۰۲۰ and ۲۰۲۳ reveal significant geographic disparities in resistance patterns, with developed countries generally having more robust healthcare systems but still facing rising rates of resistance, particularly to common antibiotics like penicillin, macrolides, and fluoroquinolones. To combat the growing threat of antibiotic resistance, the study emphasizes the importance of strengthening antibiotic stewardship programs in pediatric care settings. This includes promoting responsible antibiotic prescribing, improving diagnostic techniques to distinguish bacterial from viral infections, and enhancing surveillance of resistance trends. Without these coordinated efforts, the global threat of antimicrobial resistance, particularly in vulnerable populations like children, will only intensify, undermining the effectiveness of antibiotics and jeopardizing future public health.

کلیدواژه ها

Antibiotic resistance pediatric populations, COVID-۱۹ meta-analysis, Resistance Patterns

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