Antimicrobial Potential of Satureja Species: A Review of Bioactive Compounds and Molecular Mechanisms

  • سال انتشار: 1403
  • محل انتشار: دوفصلنامه بیوتکنولوژی گیاهی، دوره: 7، شماره: 3
  • کد COI اختصاصی: JR_PBP-7-3_005
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 96
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نویسندگان

Ahdiyeh Saghabashi

Department of Microbiology, Faculty of Sciences, Agriculture and Modern Technology, Shiraz Branch, Islamic Azad University, Shiraz, Iran

Atena Sadeghi

Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran

Mohammad Ghodratie

Department of Medical Microbiology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.

Hosna hatami

Department of medical biotechnology, Kermanshah university of medical science, Kermanshah,Iran

Seyedeh Faride Alavi Rostami

Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University Tehran-North Branch, Tehran, Iran.

Mahdi Yazdehi

۳ Department of Medical Microbiology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.

Ebrahim Mahmoudi

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Saina Najafi

Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Zahra Mottaghiyan

, Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran

چکیده

Objective: The genus Satureja (Lamiaceae), commonly referred to as savory, has been traditionally valued for its medicinal properties, particularly its antimicrobial activity. Methodology: Methodology: In this review study, the key words satureja, antimicrobial resistance, antibiotics, carvacrol, thymol, multidrug-resistant were used to search for articles. Databases such as Google Scholar, SID, Magiran, PubMed, Scopus were used for searching. Results: Various species of Satureja are rich in bioactive compounds such as thymol, carvacrol, and terpenoids, which exhibit strong antibacterial, antifungal, and antiviral properties. These essential oils primarily act by disrupting bacterial cell membranes, inhibiting biofilm formation, and interfering with bacterial metabolism and DNA replication. This review critically examines the antimicrobial properties of nine Satureja species, focusing on their bioactive compounds, molecular mechanisms, and potential applications. Conclusion: Given the growing challenge of antimicrobial resistance (AMR), the therapeutic potential of Satureja is discussed in the context of alternative antimicrobial strategies and industrial applications.

کلیدواژه ها

Satureja, Antimicrobial resistance, Antibiotics, Carvacrol, Thymol, Multidrug-resistant

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