Malignant Ovarian Mixed Germ Cell Tumor with High-risk Pathology in a Young Woman: Review of Literature
- سال انتشار: 1404
- محل انتشار: فصلنامه زنان و مامایی و سرطانهای زنان، دوره: 10، شماره: 1
- کد COI اختصاصی: JR_JOGCR-10-1_012
- زبان مقاله: انگلیسی
- تعداد مشاهده: 114
نویسندگان
Department of Gynecology Oncology, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran
Department of Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Preventive Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Gynecology Oncology, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
Department of Gynecology Oncology, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran
Department of Radiology, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده
Background and Aims: Since malignant germ cell tumors (MGCTs) are more frequent in young women, fertility preservation and survival are two main points of management. Here, we introduce a patient with an aggressive MGCT and discuss the fertility preservation in poor prognoses and aggressive tumors. Case Presentation: A ۲۷-year-old G۱L۱ woman was admitted with bilateral ovarian mass, acute pain, and increased tumor markers. Laparotomy revealed multiple large masses. Optimal debulking and staging were performed. In the final pathology, a MGCT (immature teratoma G۲ ۶۰-۷۰% + embryonal carcinoma ۳۰-۴۰%) was reported. The patient returned for chemotherapy after a ۳۵-day gap. Before beginning the chemotherapy, aggressive growth of the tumor and multiple metastases were observed. The patient underwent chemotherapy but the tumor progressed again, and in the MRI performed after chemotherapy, diffuse peritoneal carcinomatosis and tumor growth was observed. Unfortunately, the patient expired. Conclusion: fertility preservation surgery despite optimal debulking is not always associated with a favorable prognosis in high-stage or high-risk patients. In cases of advanced and/or aggressive pathology types (IT, YST, EC), it is logical to consult with the patient and her family to abandon conservative surgery and select more radical surgery.کلیدواژه ها
fertility preservation, Malignant Mixed Tumor, MGCTs, Mixed ovarian germ cell tumorاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.