The Role of Proteins in Modulating Biocompatibility of Neural Implants
- سال انتشار: 1403
- محل انتشار: چهاردهمین کنگره دوسالانه سرامیک ایران و چهارمین کنفرانس بین المللی سرامیک ایران
- کد COI اختصاصی: ICC14_124
- زبان مقاله: انگلیسی
- تعداد مشاهده: 129
نویسندگان
Department of Materials Engineering, Faculty of Engineering, Malayer University, Malayer
Department of Materials Engineering, Faculty of Engineering, Malayer University, Malayer
Department of Materials Engineering, Faculty of Engineering, Malayer University, Malayer
چکیده
The integration of neural implants into the central nervous system presents unique challenges, primarily due to the complex interactions between implant materials and biological tissues. This article explores the pivotal role of proteins in modulating the biocompatibility of neural implants. Proteins present in the surrounding environment significantly influence the host response to implants, affecting key processes such as inflammation, cell adhesion, and tissue integration. We analyze how specific proteins can either enhance or hinder biocompatibility, with some promoting favorable cellular responses and others potentially leading to adverse effects like chronic inflammation or fibrosis. This article look at how proteins interact with the surface of the implant, adsorption kinetics and conformational changes that effect the properties of the surface. In defining these mechanisms, we gain insight into how to construct protein-altered surfaces that will increase the biocompatibility of neural prosthetic devices, which in turn will make them more efficient and safe in a clinical setting.کلیدواژه ها
Neural implant, Protein interactions, Biocompatibility, Surface modification, Tissue integration.اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.