The lack of standardized methods for evaluation the efficacy and safety of nanocariers
- سال انتشار: 1403
- محل انتشار: سیزدهمین کنفرانس بین المللی علوم و توسعه فناوری نانو
- کد COI اختصاصی: SDNCONF13_016
- زبان مقاله: انگلیسی
- تعداد مشاهده: 188
نویسندگان
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran,
Department of Psychology, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran,
Department of Biotechnology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
چکیده
Nanocarriers have emerged as promising platforms for drug delivery, offering targeted therapy and enhanced efficacy while minimizing adverse effects. Physicochemical characterisation, in vitro and in vivo research, and other metrics and assays are used to assess the safety and efficacy of nanocarriers. However, the translation of these technologies from bench to bedside is hindered by the lack of standardized methods for evaluating their efficacy and safety. Variations in reported results restrict interpretation and validation in nanocarrier research and development due to the absence of uniform evaluation techniques. This paper reviews the current landscape of nanocarrier evaluation methodologies, highlights the challenges posed by the absence of standardization, and proposes detailed strategies to address this crucial issue. Standardized evaluation protocols are essential to ensure reproducibility, comparability, and regulatory approval, thus accelerating the clinical translation of nanocarrier-based therapies.کلیدواژه ها
nanocarriers, drug delivery, efficacy, safety, standardization, evaluation methods”.مقالات مرتبط جدید
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