Spectroscopic Screening of Dexamethasone and Cyproheptadine Adulteration in Weight Gaining Products Marketed in Aden, Yemen
- سال انتشار: 1403
- محل انتشار: مجله اعتیاد و سلامت، دوره: 16، شماره: 3
- کد COI اختصاصی: JR_AHJK-16-3_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 78
نویسندگان
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Aden University, Aden, Yemen
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Aden University, Aden, Yemen
Department of Pharmacognosy, Faculty of Pharmacy, Aden University, Aden, Yemen
چکیده
Background: Weight-gaining (WG) products are either medicine or herbal products that have been used intensively by the young and adolescents in Yemen. These products may contain undeclared potentially toxic ingredients that can lead to several health problems and diseases on long-term usage. This study was intended to evaluate the presence of some undeclared pharmaceuticals, dexamethasone (DX) and cyproheptadine (CPR), in WG products in Aden, Yemen.Methods: The detection of DX & CPR in WG products was evaluated using UV& Fourier transform infrared (FT-IR) spectroscopy. Also, phytochemical analysis was carried out for herbal products. Findings: The study indicated the presence of CPR in Tab-II, honey mixture, and capsules in the range between ۰.۱۰%-۱۰۲.۶%. A lower percentage was detected in the honey mixture and a higher percentage in Tab-۲. DX was only detected in Tab-I (۱۰۲.۸۷%).Conclusion: It can be concluded that WG products may contain undeclared amounts of DX and CPR. Stricter regulations must be implemented for the usage and distribution of these products to avoid potential long-term adverse consequences.کلیدواژه ها
Adulteration, Cyproheptadine, dexamethasone, Weight-gainاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.