Dengue Fever and Novel Detection Methods Based on Biosensors

  • سال انتشار: 1403
  • محل انتشار: مجله علوم طیور و بیماریهای طیور، دوره: 2، شماره: 4
  • کد COI اختصاصی: JR_JPSAD-2-4_006
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 131
دانلود فایل این مقاله

نویسندگان

Mahsa Kalantar

PhD Student of Nanobiotechnology, Faculty of Bioscience Engineering, College of Interdisciplinary Science and Technologies, University of Tehran.

Ali Hossein Rezayan

Professor, Faculty of Bioscience Engineering, College of Interdisciplinary Science and Technologies, University of Tehran.

Hassan Hajghaseem

Associate Professor, Faculty of Intelligent Systems, College of Interdisciplinary Science and Technologies, University of Tehran.

چکیده

Dengue fever, a mosquito-borne viral infection, poses a significant global health threat, and early diagnosis is crucial for effective disease management. Infection of humans usually occurs through infected Aedes mosquitoes such as Aedes aegypti or Aedes albopictus with the dengue fever virus. The spectrum of disease ranges from asymptomatic infection and mild febrile illness (dengue fever) to more serious symptoms such as dengue hemorrhagic fever and dengue shock syndrome. Dengue fever is characterized by severe headache, high fever, skin rash, muscle and joint pain, nausea, and vomiting. Dengue hemorrhagic fever is characterized by high fever, an enlarged liver, hemorrhagic phenomena, shock, and often cardiovascular disorders. Dengue fever is transmitted through urban bicycle (human transmission cycle) and Sylvatic (animal transmission cycle). The demand for early detection of this virus has increased to control the spread of infectious diseases and protect humankind from its harmful effects. For laboratory diagnosis of this virus, various methods can be employed to detect the virus itself, viral nucleic acids, antibodies, or antigens, or a combination of these approaches can be used. Recently, biosensors have been found to be a potential tool to detect and quantify the virus with fast detection, relatively cost-effective, high sensitivity, and selectivity compared to conventional diagnostic methods such as immunological and molecular techniques. Mostly, biosensors employ electrochemical detection techniques with transducers, owing to their easy construction, low cost, ease of use, and portability.Dengue fever, a mosquito-borne viral infection, poses a significant global health threat, and early diagnosis is crucial for effective disease management. Infection of humans usually occurs through infected Aedes mosquitoes such as Aedes aegypti or Aedes albopictus with the dengue fever virus. The spectrum of disease ranges from asymptomatic infection and mild febrile illness (dengue fever) to more serious symptoms such as dengue hemorrhagic fever and dengue shock syndrome. Dengue fever is characterized by severe headache, high fever, skin rash, muscle and joint pain, nausea, and vomiting. Dengue hemorrhagic fever is characterized by high fever, an enlarged liver, hemorrhagic phenomena, shock, and often cardiovascular disorders. Dengue fever is transmitted through urban bicycle (human transmission cycle) and Sylvatic (animal transmission cycle). The demand for early detection of this virus has increased to control the spread of infectious diseases and protect humankind from its harmful effects. For laboratory diagnosis of this virus, various methods can be employed to detect the virus itself, viral nucleic acids, antibodies, or antigens, or a combination of these approaches can be used. Recently, biosensors have been found to be a potential tool to detect and quantify the virus with fast detection, relatively cost-effective, high sensitivity, and selectivity compared to conventional diagnostic methods such as immunological and molecular techniques. Mostly, biosensors employ electrochemical detection techniques with transducers, owing to their easy construction, low cost, ease of use, and portability.

کلیدواژه ها

Dengue Fever, Aedes Mosquito, Clinical Symptoms, Diagnosis, Electrochemical Biosensor, Viral Disease.

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.