Association between BMI and Leptin Levels in Women with Primary Infertility: A Cross-Sectional Study
- سال انتشار: 1403
- محل انتشار: فصلنامه زنان و مامایی و سرطانهای زنان، دوره: 9، شماره: 5
- کد COI اختصاصی: JR_JOGCR-9-5_003
- زبان مقاله: انگلیسی
- تعداد مشاهده: 146
نویسندگان
Department of Obstetrics and Gynecology, Maternal Fetal and Neonatal Research Center, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran
Department of Maternal Fetal Medicine, Tehran University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Maternal Fetal and Neonatal Research Center, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Yas Hospital. Tehran University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Pasteur Hospital, Bam University of Medical Sciences, Bam, Iran
Department of Maternal Fetal Medicine, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Reza Sedighi Darijani
Department of Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Department of Medicine, School of Medicine, Yazd Branch, Islamic Azad University, Yazd, Iran
چکیده
Background & Objective: Primary infertility affects a significant proportion of couples and is often attributed to female factors. Obesity, which is associated with increased levels of the hormone leptin, is a known risk factor for female infertility. The present study was conducted with aim to investigate the association between BMI and leptin levels in females with primary infertility.Materials and Methods: This cross-sectional study was performed on ۱۰۰ women with primary infertility at Al-Nuaman Hospital and Al-Salama private hospital from September ۲۰۲۲ to March ۲۰۲۳. The participants were divided into four groups: Group ۱ (normal weight, fertile), Group ۲ (overweight infertile), Group ۳ (obese infertile), and Group ۴ (severely obese infertile) women, each consisting of ۲۵ participants, categorized based on their BMI: normal BMI (۱۸.۵–۲۴.۹ kg/m²), overweight BMI (۲۵–۲۹.۹ kg/m²), obesity BMI (≥۳۰ kg/m²), and severely obese BMI (۳۵-۴۰ kg/m²). The mean leptin levels were compared between the four groups using ANOVA, and the association between BMI and leptin levels was assessed using Pearson's correlation coefficient.Results: There was a highly significant correlation between primary infertility and the parameters (BMI and leptin) (P< ۰.۰۰۱) and showed a positive correlation between leptin and BMI.Conclusion: It was shown that females with primary infertile and a high BMI have elevated serum leptin levels. This underscores the importance of weight management in addressing primary female infertility.کلیدواژه ها
Body Mass Index, Leptin, Primary infertility, Female infertilityاطلاعات بیشتر در مورد COI
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