Review of CRISPR/Cas systems and its different applications

  • سال انتشار: 1403
  • محل انتشار: دومین کنگره بین المللی علوم، مهندسی و فن آوری های نو
  • کد COI اختصاصی: SECONGRESS02_248
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 271
دانلود فایل این مقاله

نویسندگان

Seyedeh Parya Faroud

MSc Graduated student, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

Ezzatollah Fathi

Professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

Raheleh Farahzadi

Assistant Professor, Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

چکیده

With increasing human population in the world and climate change challenges, it is essential to produce global need for food and upgrade the quantity and trait of crops. Regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein ۹ (Cas۹) technology as an influential tool in genetic engineering, had remarkable results in medicine, biotechnology, regulation of specific genes, genetic modifications of crops in agriculture and more diverse applications in breeding plants with rich nutritional value, stress tolerant crops or disease resistance products. By using CRISPR/Cas technology, genetic code in almost any organisms can be rewritten which has been employed in various cell lines. CRISPR repeats have been represented in most archaeal and bacterial genomes as part of their immune system but these repeats have not been discovered in DNA sequences of eukaryotes. Here we briefly review CRISPR technology and its’ potentials in genome editing and have a discourse on limitations and developments of this technology.

کلیدواژه ها

genome engineering, genome editing, CRISPR, Cas۹

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.