Evaluation of salivary immunoglobulin A level in thalassemic patients with periodontitis in comparison with thalassemic patients with healthy periodontium
- سال انتشار: 1395
- محل انتشار: مجله بهداشت دهان و دندان و اپیدمیولوژی دهان و دندان، دوره: 5، شماره: 4
- کد COI اختصاصی: JR_JOHOE-5-4_006
- زبان مقاله: انگلیسی
- تعداد مشاهده: 138
نویسندگان
Assistant Professor, Oral and Dental Diseases Research Center AND Kerman Social Determinants on Oral Health Research Center AND Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
Assistant Professor, Department of Periodontics, School of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran
Assistant Professor, Oral and Dental Diseases Research Center AND Kerman Social Determinants on Oral Health Research Center AND Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran
چکیده
BACKGROUND AND AIM: This study was conducted to evaluate salivary immunoglobulin A (IgA) level in thalassemic patients with periodontitis in comparison to thalassemic patients with healthy periodontium.METHODS: Seventy-five patients were included in this study and were divided into three groups, group A: ۲۵ major thalassemic patients with mild to moderate periodontitis, group B: ۲۵ thalassemic patients with healthy periodontium, and group C: ۲۵ systemically healthy people with normal periodontium. To measure salivary IgA levels, stimulated saliva was collected and analyzed by enzyme-linked immunosorbent assay (ELISA). The data were analyzed by t-test, ANOVA, and chi-square.RESULTS: Salivary IgA was significantly different in major thalassemia patients with periodontitis (۶۹ µm/ml) in comparison to major thalassemia patients with healthy periodontium (۸۱ µm/ml) (P < ۰.۰۵). The highest level of salivary IgA was observed in the systemically healthy people with normal periodontium (۸۸ µm/ml).CONCLUSION: The levels of salivary IgA were decreased in major thalassemia patients with periodontitis and healthy periodontium in comparison to systemically healthy people with normal periodontium.کلیدواژه ها
Major thalassemia, Periodontitis, immunoglobulin Aاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.