Potential Effect of Opium Consumption on Controlling Diabetes and Some Cardiovascular Risk Factors in Diabetic Patients

  • سال انتشار: 1393
  • محل انتشار: مجله اعتیاد و سلامت، دوره: 6، شماره: 1
  • کد COI اختصاصی: JR_AHJK-6-1_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 65
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نویسندگان

Najmeh Rahimi

Resident, Department of Internal Medicine, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Mohamad Hossain Gozashti

Assistant Professor, Physiology Research Center, Department of Endocrinology, Kerman University of Medical Sciences, Kerman, Iran

Hamid Najafipour

Professor, Physiology Research Center, Department of Physiology, Kerman University of Medical Sciences, Kerman, Iran

Mostafa Shokoohi

Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

Hamid Marefati

Assistant Professor, Department of Exercise Physiology, School of Physical Education and Sport Sciences, Shahid Bahonar University of Kerman AND Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran

چکیده

Background: Due to this belief that opium may have beneficial effects on diabetes or cardiovascular risk factors, the present study aimed to assess the potential and possible effects of opium consumption on diabetes control and some cardiovascular risk factors in diabetic patients. Methods: This study enrolled ۳۷۴ diabetic subjects from diabetes care centers in Kerman, Iran including opium user group (n = ۱۷۹) and a non opium user group (n = ۱۹۵). The data were collected through a questionnaire completed by interviewing, physical examination and laboratory assessment. Findings: Opium did not show any statistically significant effect on blood glucose, glycated hemoglobin (HbA۱C), fasting blood sugar (FBS), low-density lipoprotein (LDL) and diastolic blood pressure. However, systolic blood pressure and prevalence of high systolic blood pressure were significantly higher in opium user group (P < ۰.۰۵۰). In addition, lower serum high-density lipoprotein (HDL) and frequency of lower HDL was significantly higher in opium user group (P < ۰.۰۰۱). Conclusion: According to this study, opium does not seem to have beneficial effects on diabetes control or cardiovascular risk factors. Therefore, it would not be advisable to consume opium as an anti-diabetes or cardioprotective agent.

کلیدواژه ها

Opium, Diabetes Mellitus, Cardiovascular risk factor, Dyslipidemia, Hypertension

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