The Pathological Characteristics of Cervical Conization and Cervical Intraepithelial Cancer Recurrence Rate Based on Different Age Groups
- سال انتشار: 1403
- محل انتشار: فصلنامه زنان و مامایی و سرطانهای زنان، دوره: 9، شماره: 4
- کد COI اختصاصی: JR_JOGCR-9-4_013
- زبان مقاله: انگلیسی
- تعداد مشاهده: 152
نویسندگان
Department of Obstetrics and Gynecology, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
Department of Gynecology Oncology, Imam Khomeini Hospital Complex, Vali-E-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
Vali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
چکیده
Background & Objective: Immunosuppression, HPV persistence, and smoking are the main-related risk factors of Cervical Intraepithelial Neoplasia (CIN) recurrence. However, age as a basic factor may be a main factor related to CIN recurrence. Therefore, our study aimed to detect the potential role of women's age in CIN recurrence.Materials & Methods: This cross-sectional study was conducted on ۳۲۹ patients who underwent conization in the gynecology-oncology clinics of Arash and Imam Khomeini hospitals affiliated with Tehran University of Medical Sciences between March ۲۰۱۶ and March ۲۰۲۱.Results: Totally, ۳۲۹ cases were enrolled in the study. Most women were in their thirties. CIN recurrence was about ۱۰.۰% (۳۲ cases). The CIN recurrence rate was ۸.۹% in women younger than ۳۰, ۱۰.۲% in ۳۰-۴۰, ۱۱.۳% in ۴۰-۵۰, and ۵.۶% in ۵۰–۶۰ decades. There was no significant (p-value=۰.۸۰۲) difference in recurrence rate among age groups. There was a significant (p-value=۰.۰۲۳) difference in the frequency of endocervical involvement regarding age category, women aged ۴۰ to ۵۰ had the most frequent marginal involvement with ۲۶.۸%, while there was no significant (p-value=۰.۸۰۲) difference in frequency of marginal involvement regards age category.Conclusion: CIN cases with age higher than ۴۰ years need to have more caution and tight follow-up visit after conization.کلیدواژه ها
Conization, age groups, Prognosis, Recurrence, Uterine Cervical Neoplasmsاطلاعات بیشتر در مورد COI
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