Fatemeh Rezaei - Master of Pharmacy, Charles University, Czech Republic

The discovery and production of antibiotics is one of the most important findings of human knowledge. Making drugs that prevent or treat microbial infections is one of the main advances in improving the quantity and quality of life in recent years. Antimicrobial drugs are one of the most widely used types of drugs, which can be life-saving if they are used correctly, and at the same time, their incorrect and inappropriate use will increase the cost, cause side effects and interactions, and drug resistance.Today, antibiotic resistance is a problem that the world is facing. One of the important causes of antibiotic resistance is excessive and incorrect use of the antibiotics. Exposure to antimicrobial agents allows resistant bacteria to survive and antibiotic resistance is created by natural selection. The number of diseases caused by bacteria resistant to antibiotics is constantly increasing. Various methods have been used to prevent and deal with antibiotic resistance, including the combined use of drugs and destroying the defense barriers of bacteria. Also, the use of nanoparticles has a synergistic effect on the performance of antibiotics and causes the destruction of antibiotic-resistant bacteria. In this study, possible strategies for optimizing antibiotic consumption and also reducing the risk of inducing bacterial resistance have been investigated.

Antibiotic, Antibiotic resistance, Nanoparticles