Dynamics of TMAFM in Liquid: Application to Molecular Metrology and Biological Sciences

سال انتشار: 1389
محل انتشار: هفدهمین کنفرانس مهندسی پزشکی ایران
کد COI اختصاصی: ICBME17_211
زبان مقاله: انگلیسی
تعداد مشاهده: 977

نویسندگان

Robotic Research Laboratory, College of Mechanical Engineering, Iran University of Science and Technology,Tehran, Iran

چکیده

Application of atomic force microscopy (AFM) in liquid is necessary for imaging and manipulation of biologicalspecimens. The atomic force microscope (AFM) has become an indispensable tool in biology because it permits the imaging and probing of nanomechanical properties of biological samples such as biopolymers and viruses under physiological (liquid environments) conditions. In this paper, we have simulated a tapping-mode AFM (TMAFM) cantilever in liquid environment near a surface. Contact forces have some differences in liquid incomparison to air or vacuum in magnitude or formulation. Hydrodynamic forces are also applied on the cantilever due to the motion in liquid. For modeling we have used a continuous beam model with its first mode and forward-time simulation method for simulation of its hybrid dynamics. The results show a good agreement with experiments. They also show that the effect of separation on free vibration amplitude is great. Its effect onresonance frequency is considerable too. The resonance frequency in liquid is so small in comparison to air due toadditional mass and also additional damping created by the viscosity of the liquid around.

کلیدواژه ها

Tapping-mode atomic force microscopy (TMAFM),Liquid, imaging, hydrodynamic forces

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.