Frontiers and therapeutic applications of poly (ε-caprolactone): Tissue engineering, medical implants, microbial infections, diabetic wounds, and cancers
- سال انتشار: 1403
- محل انتشار: مجله جنبه های زیستی میکرو نانو، دوره: 3، شماره: 3
- کد COI اختصاصی: JR_MNBA-3-3_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 97
نویسندگان
Department of Biological Science, Faculty of Science, University of Kurdistan, Sanandaj, Kurdistan, Iran
Department of Food Microbiology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
Louisiana Tech University: Ruston, USA
چکیده
Synthetic and natural polymers as important biomaterials have achieved great interest in a variety of biomedical and pharmaceutical fields. Among the synthetic polymers, the bioactive properties of poly (ε-caprolactone) (PCL) polymer favor its application in biomedical and pharmaceutical applications. This synthetic polymer as a versatile platform has been applied in tissue engineering and medical implants as three-dimensional scaffolds and in microbial infections, diabetic wounds, and cancers as drug micro- and nanocarriers. As the major benefits, PCL has illustrated cost-effective, easy availability, biocompatibility, biodegradability, and mechanical features with simple modification. However, this polymer has shown poor hydrophilicity and a long degradation cycle as clinical limitations, which can be improved by novel formulations of PCL with synthetic and natural biomaterials.کلیدواژه ها
Bioactive Materials, PCL polymer, Three-dimensional scaffolds, Nanocarriersاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.