Roman Roitman - Head of the Laboratory of Energy of Biological Systems, Institute of Theoretical and Experimental RA
Wolfgang Schatton - Head of the Laboratory of Energy of Biological Systems, Institute of Theoretical and Experimental RA
Evgeny Ilyich Maevsky - Head of the Laboratory of Energy of Biological Systems, Institute of Theoretical and Experimental RA

Globally recommended diets are a powerful method for raising the public's awareness of dietary choices. Although dietary choices drive both health and environmental outcomes, these diets make almost no reference to environmental impacts. Besides, Encephalic damage and disorders of the hepatobiliary system occur against the background of metabolic disorders. Metabolic processes largely depend on the activity and the qualitative and quantitative characteristics of sirtuin-type proteins. Protein deficiency can be filled by artificially introducing them into the body through dietary supplements. The study aimed to analyze the possibilities of using the dietary supplement OYOX to prevent environmental harm as well as treating encephalic damage and disorders of the hepatobiliary system. We used theoretical and practical research methods. In particular, the methods of analysis of literature sources, statistical data, results of clinical and preclinical studies were used. The method of generalization, analysis, systematization, classification of the obtained data was used. The results were evaluated ۳ and ۶ months after taking the dietary supplement. In the group of people taking OYOX, a statistically significant decrease was observed in the percentage of short telomeres (p = ۰.۰۲۹); a decrease in the percentage of senescent cytotoxic (CD۸+ / CD۲۸-) T cells (by ۱.۵%; ۴.۴%; ۸.۶% and ۷.۵% after ۳ and ۶ months respectively); improvement in lipid and carbohydrate metabolism glycosylated hemoglobin (HbA, ۱%) by ۴.۹% (p = ۰.۰۱), total cholesterol ۵.۷ mmol  L-۱ (p = ۰.۰۰۳), low density lipoprotein (LCL-C): ۳.۸۲ mmol  L-۱ (p = ۰.۰۰۲۱), homocysteine: ۳.۴ mmol L-۱  (p = ۰.۰۰۱). In conclusions, dietary supplement OYOX is effectively used to eliminate the deficiency of sirtuin-type proteins SIR۱, SIR۳, SIR۶.

Encephalic damage, Environmental damage, Nutrigenomic preparation, Orthomolecular composition, OYOX, Sirtuin-type Proteins