Seksenova Dana Uzakovna - Abai Kazakh National Pedagogical University, Almaty, Republic of Kazakhstan, Kazakhstan
Maimatayeva Asiya Duysengalievna - Abai Kazakh National Pedagogical University, Almaty, Republic of Kazakhstan, Kazakhstan
Issayev Gani Isaulu - Khoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Republic of Kazakhstan, Kazakhstan
Atalikhova Gulfairuz Bisenovna - Atyrau State University Named after Kh. Dosmukhamedov, Atyrau, Kazakhstan
Ibragimova Elmira Konratbayevna - Khoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan, e-mail: Elmira, Kazakhstan
Yessimov Bolat Kabdushevich - Biology Department of Abai KazNPU, Almaty, Kazakhstan

Sarcosporidia and sarcosporidiosis in Southeast Kazakhstan present formidable challenges to livestock health. This paper focuses on the outcomes of two key innovations: advancements in molecular diagnostics and the development of integrated control strategies. In the realm of diagnostics, the implementation of Polymerase Chain Reaction (PCR) techniques for species-specific identification and quantification yielded notable results. Our comprehensive survey of vertebrates in the region identified a diverse range of Sarcosporidia species, with an average prevalence reduction of ۲۵% compared to conventional methods. This advancement not only enhances accuracy in parasite identification but also provides a more nuanced understanding of the local epidemiological landscape. The integration of Geographic Information System (GIS) and remote sensing technologies into our surveillance system revealed specific high-risk areas with an unprecedented precision of ۹۰%. This targeted approach allowed for resource optimization, resulting in a ۳۰% reduction in overall prevalence rates in the identified regions. The practical implications of this innovation are evident in its potential to guide effective intervention strategies and resource allocation. Genomic studies elucidated the genetic diversity within Sarcosporidia strains, laying the foundation for targeted interventions. Building on this knowledge, preliminary trials of our integrated control strategies showcased a promising ۴۰% reduction in Sarcosporidia prevalence in the selected communities. This innovative approach combines traditional deworming practices with environmentally friendly treatments, providing a viable and sustainable solution. In conclusion, our research signifies a substantial leap forward in understanding and combating Sarcosporidia infections in Southeast Kazakhstan. The tangible results of improved diagnostics and the promising outcomes of integrated control strategies underscore the potential for transformative impacts on livestock health, agricultural productivity, and the well-being of the communities reliant on these animals.

Diagnostics, Integrated Control, Kazakhstan, Molecular Techniques, Sarcosporidia