Akram Kooshki - Non-Communicable Diseases Research Center, Department of Nutrition & Biochemistry, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
Mohammad Reza Memarzadeh - Barij Medicinal Plants Research Center, Kashan, Iran
Mohammad Hassan Rakhshani - Department of Environmental Health, School of Health, Sabzevar University of Medical Sciences, Sabzevar, Iran
Roya Akbarzadeh - Department of Anesthesiology, Faculty of Paramedical, Sabzevar University of Medical Sciences, Sabzevar, Iran
Tahereh Tofighiyan - Department of Nursing, School of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran
Elaheh Foroumandi - Non-Communicable Diseases Research Center, Department of Nutrition & Biochemistry, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran

Objective: This study assessed the effects of Aloe verasupplementation on serum inflammatory factors, blood sugar andlipid profiles in hemodialysis patients.Materials and Methods: Totally, ۵۰ hemodialysis patients wereallocated randomly to either Aloe vera or placebo groups. TheAloe vera group received ۲ Aloe vera capsules daily for ۸ weeks(۵۰۰ mg/day). Serum C-reactive protein (hs- CRP), Fasting bloodglucose (FBS), and lipid profiles levels were evaluated at thebaseline and the end of the eighth week.Results: Aloe vera supplementation for ۸ weeks was associatedwith a significant reduction of serum hs- CRP (p=۰.۰۰۴), totalcholesterol (p=۰.۰۱), low density lipoprotein (LDL) (p=۰.۰۲) levesand increased high density lipoprotein (HDL) (p=۰.۰۰۲)concentration in the hemodialysis patients.Conclusion: Aloe vera supplementation is beneficial inimprovement of cardiovascular risk factors in hemodialysispatients

Aloe vera, C-reactive protein, Inflammation, Lipids, hemodialysis