Platelet-Rich Plasma Effect in Femoral Head Osteotomy Outcome: A Systematic Review

سال انتشار: 1403
محل انتشار: فصلنامه پیشرفت درتحقیقات بیوشیمی و شیمی، دوره: 7، شماره: 2
کد COI اختصاصی: JR_PCBR-7-2_005
زبان مقاله: انگلیسی
تعداد مشاهده: 22

نویسندگان

Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

چکیده

Introduction: This systematic review seeks to assess the impact of platelet-rich plasma (PRP) on the outcomes of femoral head osteotomy and aims to evaluate platelet-rich plasma effect in femoral head osteotomy outcome.Material and methods: A comprehensive exploration of electronic databases, encompassing PubMed, Embase, and the Cochrane Library will be conducted (۲۰۰۰-۲۰۲۳). The search strategy will be tailored to unearth pertinent studies published up to the current date, with no restrictions on language. The search terms will encompass various combinations and variations of keywords related to "platelet-rich plasma", "femoral head osteotomy", "hip disorders", and "clinical outcomes".Results: This articles published in ۲۰۱۳-۲۰۲۱.The primary outcomes assessed in the included studies were pain scores (p˂۰.۰۵), functional assessments (p˂۰.۰۵), radiographic findings (p˂۰.۰۵), and patient-reported outcomes (p˂۰.۰۵). Secondary outcomes included range of motion (p˂۰.۰۵), complications (p˂۰.۰۵), and adverse events (p˂۰.۰۵). However, the reporting of outcomes varied across the studies, making direct comparisons challenging.Conclusion: This systematic review reveals a potential positive impact of PRP on femoral head osteotomy outcomes. The use of PRP is linked with enhanced pain relief, functional improvements, positive radiographic findings, and favorable patient-reported outcomes. Nonetheless, the heterogeneity presence across the included studies, limited outcome reporting, and the potential for publication bias underscore the need for cautious interpretation of the results.

کلیدواژه ها

Platelet-Rich Plasma, Femoral Head Osteotomy, outcome

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