Effect of adding CPP-ACP into a daily-use toothpaste on remineralization of enamel white spot lesions
- سال انتشار: 1403
- محل انتشار: مجله مواد و تکنیک های دندانپزشکی، دوره: 13، شماره: 1
- کد COI اختصاصی: JR_JDMT-13-1_001
- زبان مقاله: انگلیسی
- تعداد مشاهده: 67
نویسندگان
School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
School of Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Private Practice, Mashhad, Iran
Aliakbar Hodjatpanah Montazeri
Private Practice, Mashhad, Iran
Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده
Objective: The purpose of this study was to investigate the effect of adding CPP-ACP into a daily-use toothpaste on the remineralization of enamel caries lesions.Methods: Thirty enamel blocks were obtained from bovine incisors. Each specimen was divided into three equal parts. One-third of each block was coated with varnish to serve as a sound control area, while the remaining two-thirds underwent a demineralization process. After demineralization, another one-third of the surface was varnished, leaving only one-third of the enamel to undergo remineralization. The enamel blocks were divided into three groups (n=۱۰), according to the remineralization treatment applied as follows: Group ۱: fluoride-containing toothpaste, Group ۲: CPP-ACP-containing toothpaste, and Group ۳: fluoride- and CPP–ACP–containing toothpaste. Remineralization was assessed through the Vickers microhardness test at various depths (۲۰, ۵۰, ۱۲۰ and ۲۰۰ µm). The data were analyzed by ANOVA and LSD test, and P< ۰.۰۵ was considered statistically significant.Results: There was a significant difference in remineralization efficacy between the groups at the depth of ۲۰ µm (P ۰.۰۰۱). Pairwise comparisons revealed that the toothpaste containing both fluoride and CPP-ACP had a significantly greater microhardness than other experimental groups (P ۰.۰۵). No significant difference was observed between the study groups concerning microhardness at ۵۰, ۱۲۰ and ۲۰۰ µm depths (P ۰.۰۵).Conclusions: CPP-ACP can serve as a suitable alternative to fluoride in daily-use toothpaste for enamel remineralization. The concurrent use of fluoride and CPP-ACP in toothpaste can generate a synergistic remineralizing effect at the enamel surface layer.کلیدواژه ها
CPP-ACP, dental enamel, Fluoride, Remineralization, toothpaste, White spot lesionاطلاعات بیشتر در مورد COI
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