Prevalence of hepatitis C among thalassemic patients reffering to Kerman university of medical sciences hospital NO:۱ in ۱۹۹۶
- سال انتشار: 1379
- محل انتشار: مجله دانشگاه علوم پزشکی کرمان، دوره: 7، شماره: 3
- کد COI اختصاصی: JR_JKMU-7-3_002
- زبان مقاله: فارسی
- تعداد مشاهده: 73
نویسندگان
Assistant professor
Assistant professor
چکیده
this prospective case-control study was carried out to evaluate the Prevalence of positive cases of anti-HCV Ab in ۱۰۷ thalassemic patients and ۱۰۷ children without any previous history of blood transfusion as a control group.ELISA GENERATION II was used for serologic investigation and then positive cases were confiemed by RIBA generation I.the average age of thalassemic patients was ۹.۲+_۴.۳ years and those of control group was ۸.۹+_۴.۲ years.۴۵.۱% of the case group and ۳۹.۲% of the control group were female and ۵۴.۹% of the case group and ۶۰.۸% of the control group were male.Anti-HVC Ab was positive in ۲۲.۴% of the thalassemic patients while there was no positive case in the control group and the difference was statistically significant(p< ۰.۰۰۱).the average number of transfusions was ۱۰۴+_۵۸.۲ in anti-HCV Ab positive thalassemic patients and ۸۵.۳+_۵۰.۶ in anti-HCV Ab negative patients and the difference was not statistically significant(p=۰.۱۲۶).According to the results of this study,the prevalence of contamination with HCV was zero in normal population of Kernanian children and ۲۲.۴% in thalassemic patients.therefore screening of donated bloods for anti-HCV Ab in order to eliminate the contaminated bloods has a significant bimportant in preventing HCV transmission in highrisk group.کلیدواژه ها
thalassemic, Hepatitis C, anti-HCV Ab, Blood transfusionاطلاعات بیشتر در مورد COI
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