Frequency of Toxoplasma gondii, Rubella, and Cytomegalovirus Antibodies in Pregnant Women in Yazd Province, Iran
- سال انتشار: 1402
- محل انتشار: میکروبیولوژی بالینی و عفونت، دوره: 10، شماره: 4
- کد COI اختصاصی: JR_JCMI-10-4_003
- زبان مقاله: انگلیسی
- تعداد مشاهده: 32
نویسندگان
چکیده
Background: TRC (Toxoplasma gondii, rubella virus, and cytomegalovirus [CMV]) infections during pregnancy can lead to serious sequelae in the uterine fetus. Prenatal testing, which includes screening and diagnosis of antibodies to TRC infections, is one of the most important aspects of prenatal care recommended during pregnancy. The aim of the present study was to determine the seroprevalence of TRC infections in pregnant women who attended the antenatal clinic in Yazd province in central Iran. Methods: For this purpose, ۸۳۵۵ sera samples were obtained from pregnant women attending the central laboratory of Yazd province in central Iran and subjected to screening for immunoglobulin G (IgG) and IgM antibodies against TRC using the enzyme-linked immunosorbent assay method. Of these, ۴,۲۴۵, ۲,۱۹۰, and ۱,۹۲۰ pregnant women were screened for anti-Toxoplasma, rubella, and CMV, IgG, and IgM antibodies, respectively. Results: The results revealed that ۷۷.۴% (۱۶۹۵/۲۱۹۰) and ۷۸.۱% (۱۵۰۰/۱۹۲۰) were positive for anti-rubella and anti-CMV IgG antibodies, and n.o seropositive was detected for anti-rubella and -CMV IgM antibodies. For anti-Toxoplasma antibodies, ۲۰.۸۵% (۸۸۵/۴۲۴۵), ۹.۵۴% (۴۰۵/۴۲۴۵), and ۱۲.۰۱% (۵۱۰/۴۲۴۵) were positive for IgG, IgM, and both IgG-IgM antibodies, respectively. In addition, our findings showed the high prevalence of chronic TRC infections and a low recently acquired Toxoplasma infection in pregnant women. Conclusion: Our findings confirmed the high prevalence of chronic TRC infections and a low recently acquired Toxoplasma infection in pregnant women. Hence, observing personal behavioral practices (the source of infection and hygienic measures) are recommended to women at reproductive-age in general and seronegative pregnant women in particular.کلیدواژه ها
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