Antibacterial activity of the sea cucumber Holothuria leucospilota
- سال انتشار: 1392
- محل انتشار: مجله بین المللی میکروبیولوژی مولکولی و بالینی، دوره: 3، شماره: 1
- کد COI اختصاصی: JR_IJMCM-3-1_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 149
نویسندگان
Department of Fisheries, Faculty of Natural Resources, University of Tehran, Karaj, Iran.
Department of Fisheries, Faculty of Natural Resources, University of Tehran, Karaj, Iran.
Iranian Fisheries Research Institute, Tehran, Iran.
Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Iranian Fisheries Research Institute, Tehran, Iran.
Department of microbiology, Faculty of medicine, Golestan University of medical science, Gorgan, Iran.
Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
چکیده
Aquatics are a source of bioactive compounds that these compounds have different properties such as antimicrobial activity. In this study, antibacterial activity of methanol, chloroform and hexane extracts from body wall, gonad and intestine of sea cucumber Holothuria leucospilota was evaluated against Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus. Bioactive compounds of body wall, gonad and intestine of the sea cucumber Holothuria leucospilota collected from the north coast of the Persian Gulf were extracted using methanol, chloroform and hexane. The antibacterial activity was determined using the serial dilution method. The minimum inhibitory concentration and minimum bactericidal concentration was evaluated by broth micro dilution method. Results demonstrated that the P.aeruginosa was shown to be the most sensitive microorganism. All concentrations of methanol extracts from body wall, gonad and intestine did not show antibacterial activity against B.subtilis and S.aureus. Methanol extracts of gonad and intestine and chloroform extract from body wall showed no antibacterial activity against P. aeruginosa. Hexane extract from gonad had no inhibitory effect on the growth of B. subtilis in any of the concentrations. Other extracts had antibacterial effect in certain concentrations studied. None of the extracts showed any bactericidal effect against B. subtilis. Based on findings of this study, sea cucumber extracts can be considered as a natural antibiotic in the future research.کلیدواژه ها
antibacterial activity, bioactive compound, sea cucumberاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.