Antibiotic Resistance of Clinical Isolates of Acinetobacter Baumannii in Hospitals of Kermanshah, Iran during one year
- سال انتشار: 1391
- محل انتشار: مجله دانشگاه علوم پزشکی کرمان، دوره: 19، شماره: 5
- کد COI اختصاصی: JR_JKMU-19-5_010
- زبان مقاله: فارسی
- تعداد مشاهده: 108
نویسندگان
Assistant Professor of Microbiology, Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Assistant Professor of Pharmacology, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran
Pharmacologist, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
Assistant Professor of Biostatistics, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Postgraduate of Microbiology, Taleghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
چکیده
Background & Aims: Acinetobacter spp. are non-fermenting gram-negative coccobacilli that have emerged in recent three decades as major causes of nosocomial infections. Acinetobacter baumannii is the most common pathogen causing a wide spectrum of infections. Acinetobacter infections are difficult to treat, due to both the intrinsic resistance of the pathogen and its ability to readily acquire new resistance mechanisms. Methods: A total of ۸۴ Acinetobacter strains isolated from clinical samples were identified at the species level by biochemical tests. Then their susceptibility to ۲۳ antibiotics and synergism among some of them were determined using disk agar diffusion testing. Antibiogram results were interpreted by using CLSI standard tables. Results: The highest rate of drug resistance (۹۲-۹۸%) was observed to ampicillin, cefpodoxime, cefotaxime and ceftriaxone. Tigecycline, colistin and polymyxin B with the least resistance (۳-۱۴%) were identified as the most effective antibiotics. Conclusion: Non-fermentative bacteria such as Acinetobacter always are known as examples of drugresistant bacteria. The results of the present study also indicate a high level of resistance to different antibiotics. Difference in the rates of Acinetobacter resistance to antibiotics based on geographical areas was observed.کلیدواژه ها
Acinetobacter baumannii, Antibiotic Resistance, Kermanshahاطلاعات بیشتر در مورد COI
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