Evaluation of Liver Enzymes, Hematologic and Coagulation Factors in Patients with Chronic Kidney Disease
- سال انتشار: 1402
- محل انتشار: فصلنامه تحقیقات بین رشته ای در اورولوژی، دوره: 5، شماره: 4
- کد COI اختصاصی: JR_TUMS-5-4_004
- زبان مقاله: انگلیسی
- تعداد مشاهده: 112
نویسندگان
Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Department of Public Health, Asadabad School of Medical Sciences, Asadabad, Iran
Department of Public Health, School of Health, Abadan University of Medical Sciences, Abadan, Iran
Department of Pharmacology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran
Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Clinical Research Development Unit, Taleghani Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran
Department of Physiology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran
چکیده
Introduction: Chronic Kidney Disease (CKD) is a condition where the kidneys have abnormal structure or function that lasts for more than three months, can have negative health effects, and often does not show symptoms in the beginning. In that research, we tried to examine the diagnostic markers from the laboratory to find clues for a faster diagnosis of this disease.Methods: This paper is a cross-sectional analytical study on ۱۰۷ patients with CKD hospitalized in Abadan University of Medical Sciences educational hospitals from March ۲۱, ۲۰۱۷, to March ۱۹, ۲۰۲۰. Once the necessary permits were obtained, the laboratory information of patients was received from HIS. The data was analyzed by SPSS version ۱۶ software. Statistical significance is considered when P-value> ۰.۰۵.Results: Out of ۱۰۷ patients with CKD in the study, ۵۵ (۵۱.۴%) were female and ۵۲ (۴۸.۶%) were male. The mean age of the group was ۵۷.۹±۱۷.۴۲ years. The means of renal diagnostic markers such as creatinine ۷.۴۲±۴.۵۵ and BUN ۵۶.۹۷±۳۶.۷۸ were higher than normal. Also, the mean coagulation markers, including PT (۱۵.۸۶±۹.۸۹), PTT (۴۷.۶۵±۲۹.۱۱), and INR (۱.۵۴±۱.۰۷), were higher than normal. The mean of hematological diagnostic markers, including hemoglobin and hematocrit, was lower than normal. The mean RDW-CV (۱۶.۹۷±۴.۱۹) and white blood cells (۱۱.۱۹±۹.۰۱) were higher than normal.Conclusions: This study showed that renal markers (creatinine and BUN) and coagulation factors (PT, PTT, and INR) were higher than normal. In this study, it was observed that people with CKD are prone to anemia because a decrease in the mean hemoglobin and hematocrit and an increase in RDW-CV were observed.کلیدواژه ها
Kidney, Coagulation Factors, Hemoglobin, Creatinineاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.