Investigating the antibiotic resistance pattern of Escherichia coli isolates causing urinary tract infection in patients referred to Imam Khomeini Hospital in Shirvan city in the year ۲۰۲۲

  • سال انتشار: 1402
  • محل انتشار: بیست و چهارمین کنگره بین المللی میکروب شناسی ایران
  • کد COI اختصاصی: MEDISM24_371
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 71
دانلود فایل این مقاله

نویسندگان

Moein hamidi hesari

Imam Khomeini Hospital, Shirvan, North Khorasan University of Medical Sciences, Bojnurd, Iran

Maliheh Najafi

Khatam ol anbia Hospital, Shirvan, North Khorasan University of Medical Sciences, Bojnurd, Iran

Jafar hemmat

Biotechnology Department. Iranian Research Organization for Science and Technology (IROST)

چکیده

BACKGROUND AND OBJECTIVESUrinary tract infection is one of the most common bacterial infections around the world, and Escherichia coli is the most common cause of urinary tract infections in the world. Considering the increasing antibiotic resistance and since there is a direct relationship between antimicrobial levels prescribed and the level of resistance seen in a wide range of organisms. Therefore, this study was conducted with the aim of investigating the antibiotic resistance of Escherichia coli at Imam Khomeini Hospital in Shirvan.MATERIALS AND METHODSIn this cross-sectional descriptive study that was conducted from April to March ۲۰۲۲, ۲۰۸۹ urine culture samples were sent from outpatients and inpatients at Imam Khomeini Hospital in Shirvan city, ۱۲۲ samples were positive. Different bacterial culture environments as well as different biochemical tests were used to identify bacterial isolates and disc diffusion method was used to check the antibiotic resistance of Escherichia coli bacteria.RESULTS AND DISCUSSIONOut of ۱۲۲ positive samples in ۱۴۰۱, ۷۷ samples are related to Escherichia coli bacteria, of which ampicillin-sulbactam antibiotic (۶۶.۶۶%) is the most resistant and nitrofurantoin (۳.۲۲%) is the least resistant. Resistance of other antibiotics, respectively, Cefotaxime (۵۸.۹%), Cefixime (۵۷.۱%), Cefazolin (۵۱.۲۱%), Doxycycline (۴۵.۹%), Ceftazidime (۴۵%), Ciprofloxacin (۳۱%) Gentamicin (۹.۲۱%).CONCLUSIONIn general, according to the results, the most resistant antibiotics are ampicillin-sulbactam and vesofotaxime, which are recommended not to be prescribed due to their resistance and ineffectiveness in treatment. Nitrofurantoin and gentamicin are the most sensitive, respectively.

کلیدواژه ها

Urinary tract infection, Escherichia coli, antibiotic resistance

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.