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Application of WHONET in the Analysis of Pseudomonas aeruginosa Resistance to Imipenem and Meropenem

عنوان مقاله: Application of WHONET in the Analysis of Pseudomonas aeruginosa Resistance to Imipenem and Meropenem
شناسه ملی مقاله: JR_IJMM-17-5_011
منتشر شده در در سال 1402
مشخصات نویسندگان مقاله:

Rawezh Othman Ahmad - Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
Amjad Ahmadi - Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Nasrin Bahmani - Zoonoses Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
Arezou Taherpour - Department of Microbiology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran

خلاصه مقاله:
Background and Aim: WHONET software is a database for analyzing microbiology data, specifically antibiotic resistance patterns. Pseudomonas aeruginosa is a significant agent of nosocomial infections and has been identified as a critical priority by the World Health Organization (WHO). The aim of this study was to monitor the resistance patterns of imipenem and meropenem over one year (February ۲۰۲۲-February ۲۰۲۳) using WHONET software ۲۰۲۲. Materials and Methods: A total of ۹۵ P. aeruginosa isolates were obtained from Kowsar Hospital in Sanandaj, Iran. After verification through biochemical tests and ۱۶sRNA PCR, an antibiogram test was performed for each isolate based on The Clinical & Laboratory Standards Institute (CLSI) guidelines. Data were analyzed using WHONET ۲۰۲۲. Results & Conclusion: Pseudomonas aeruginosa isolates were obtained from ۴۴ females and ۵۱ males. Of all isolates, the WHONET analysis showed that resistance to imipenem and meropenem was ۸۷.۴% and ۶۴.۲%, respectively. The WHONET database can be an appropriate software for analyzing and monitoring bacterial susceptibility and resistance, especially for critical priority bugs such as P. aeruginosa.

کلمات کلیدی:
Imipenem, Meropenem, Pseudomonas aeruginosa, WHONET, سودوموناس آئروژینوزا. WHONET, ایمیپنم, مروپنم

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1920116/