Clinical, Laboratory and Imaging Characteristics of Women with Uterine Fibroid: A Cross-Sectional Study from Iran
- سال انتشار: 1403
- محل انتشار: فصلنامه زنان و مامایی و سرطانهای زنان، دوره: 9، شماره: 1
- کد COI اختصاصی: JR_JOGCR-9-1_007
- زبان مقاله: انگلیسی
- تعداد مشاهده: 162
نویسندگان
Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Preventative Gynecology Research Center, Universal Scientific Education and Research Network (USERN), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Obstetrics and Gynecology, Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Cell and Molecular Biology, School of Biological Sciences, Kharazmi University, Tehran, Iran
Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده
Background and Objective: Uterine fibroids (UFs) the most common pelvic tumors among women at reproductive age affecting women’s quality of life even their confidence with its symptoms. We designed a study to investigate the clinical, laboratory, and imaging characteristics of Iranian women with UF.Methods: This cross-sectional study was performed April ۲۰۱۶- September ۲۰۲۲ at Imam Hossein hospital (Tehran, Iran). We included all women with UF referring to the Obstetrics and Gynecology Clinic of Imam Hossein Hospital. Based on a checklist a research team interviewed the patients to investigate clinical characteristics. Also we explored laboratory and transvaginal sonography (TVS) findings of all patients. Results: The mean age of ۴۳۹ studied patients was ۴۴.۴۷±۸.۸۰ years (range: ۲۳-۸۱). The most prevalent underlying disease was hypertension (۱۷.۱%), followed by thyroid diseases (۱۵.۷%) and diabetes mellitus (۱۳.۷%). The patients mainly complained of AUB (abnormal menstrual bleeding) (۶۰.۰%), abdominal pain (۲۳.۷%). The mean NLR (neutrophil to lymphocyte ratio) and the mean PLR (platelet to lymphocyte ratio) were significantly higher than the normal upper limit (P< ۰.۰۰۱). Largest diameter of UF was ۴۹.۸۹±۴۷.۹۲ mm. Most fibroids were located anteriorly (۴۳.۱%). The multivariate linear regression model revealed that age (β=-۰.۹۳۱, ۹۵%CI= (-۱.۶۵۷, -۰.۲۰۴), P=۰.۰۱۲) and number of fibroid (β=۲۲.۴۱۸, ۹۵%CI= (۱۶.۳۶۰, ۲۸.۴۷۶), P< ۰.۰۰۱) could predict the size of fibroid. Conclusion: Our results showed that NLR and PLR were increased in UF patients. It seems that patient’s age and number of fibroid may be the predict factors for UF's size. Keywords: Abnormal Uterine Bleeding, hypertension, Neutrophil, Leiomyoma, Lymphocyte, Ultrasonography.کلیدواژه ها
Abnormal uterine bleeding, hypertension, NEUTROPHIL, Leiomyoma, Lymphocyte, Ultrasonographyاطلاعات بیشتر در مورد COI
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