Anti-inflammatory and antimicrobial activities of the successive extracts of the aerial parts of Rumex pictus Forssk. growing in Egypt
- سال انتشار: 1400
- محل انتشار: Journal of Herbmed Pharmacology، دوره: 10، شماره: 1
- کد COI اختصاصی: JR_HERM-10-1_012
- زبان مقاله: انگلیسی
- تعداد مشاهده: 98
نویسندگان
چکیده
Introduction: Rumex spp. have been used in folk medicine either as food or as medicine for the treatment of several diseases including constipation, fever, inflammation, bacterial and fungal infections. This study aimed to evaluate the anti-inflammatory and antimicrobial activities of the successive extracts of the aerial parts of Rumex pictus Forssk. growing in Egypt, and to identify the chemical constituents in the bioactive extract. Methods: Ether, chloroformic, and ۷۰% methanolic extracts of the aerial parts of R. pictus were assayed for their in vivo anti-inflammatory activity using carrageenan-induced rat hind paw edema method. These extracts were also tested for their in vitro antibacterial and antifungal activities using disc diffusion method. Results: The ۷۰% methanolic extract of R. pictus exhibited significant anti-inflammatory, antibacterial, and anti-candida activities. Thus, fractionation of the bioactive extract was performed which led to the isolation of three anthraquinones, as well as, seven flavonoids. Conclusion: Rumex pictus possesses anti-inflammatory and antimicrobial activities which reinforce its use in ethnomedicine.کلیدواژه ها
اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.