Poly(lactic acid) (PLA) Nanofibers for Bone Tissue Engineering
- سال انتشار: 1398
- محل انتشار: نشریه نساجی و پلیمر، دوره: 7، شماره: 2
- کد COI اختصاصی: JR_ITAST-7-2_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 61
نویسندگان
Department of Textile Engineering, Isfahan University of Technology, Isfahan ۸۴۱۵۶-۸۳۱۱, Iran.
Department of Textile Engineering, Isfahan University of Technology, Isfahan ۸۴۱۵۶-۸۳۱۱, Iran.
Department of Textile Engineering, Pamukkale University, ۲۰۱۶۰, Denizli, Turkey.
چکیده
Bone tissue engineering is the most promising therapeutic method to alleviate the fast-growing request for bone grafts in nonunion bone defects. It is founded on the use of implanted autologous cells or induced stem cells to form bone tissues on naturally derived or synthetic scaffolds. Nanofibers are being increasingly implemented in bone tissue engineering field as scaffolding materials to regenerate new bone tissues owing to their high surface area-to-volume ratio, high porosity with an interconnected pore structure and the suitable surface structure for cell attachment, proliferation, and differentiation. PLA biopolymer has captured the most attention and interest as a bone tissue engineering material since PLA is easily processable and degrades and disintegrates into natural metabolites while its degradation rate matches with the healing time of damaged human bone tissues. So, the potential of using PLA nanofibers in bone tissue engineering is a serious goal for scientists in novel investigations. This review gives detailed information about the recent developments and applications of PLA nanofibers as scaffolds for bone tissue regeneration.کلیدواژه ها
Nanofiber, Tissue engineering, poly(lactic acid), Bone, Scaffoldاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.