Evaluation the FLAIR Sensitivity and DWI Post-inject in Comparison with Delayed Enhancement T۱w for Better Detection of Active MS Lesions
- سال انتشار: 1397
- محل انتشار: مجله فیزیک و مهندسی پزشکی، دوره: 8، شماره: 4
- کد COI اختصاصی: JR_JBPE-8-4_004
- زبان مقاله: انگلیسی
- تعداد مشاهده: 145
نویسندگان
Department of Radiology, BSc of Radiology, School of Paramedical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran
Department of Radiology, BSc of Radiology, School of Paramedical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran
Department of Radiology, Faculty of Paramedical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran
Professor Assistant of Radiology, Kurdistan Department of Radiology, Faculty of Medical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran
MSc of Anatomy, Shahid Chamran MRI center, Kurdistan University of Medical Sciences, Sanandaj, Iran
چکیده
Background: Multiple sclerosis (MS) is a chronic, typically progressive and most common autoimmune disease which damaged the central nervous system. According to the reports in ۲۰۰۸, this disorder has affected ۲ and ۲.۵ million people globally. While the reason is not clear, proposed causes for this include immunologic, environmental, infectious and genetic factors, and sexuality. MS can cause many symptoms, including blurred vision, loss of balance, poor coordination, slurred speech, tremors, numbness, extreme fatigue, problems with memory and concentration, paralysis, blindness, and more. There are four distinguished illness fields in MS: relapsing-remitting MS (RRMS), primary-progressive MS (PPMS), secondary-progressive MS (SPMS), and progressive-relapsing. MRI is a great tool to identify the asymptomatic distribution of lesions in space and time. Materials and Methods: ۳۲ patients with MS plaques were evaluated by FLAIR and DWI pre- and post-Gadolinium injection compared with ۱۵minutes delay T۱w SE. Results: FLAIR post-inject had significantly better detection of the number and signal intensity of active MS lesions. DWI and ADC images detected active plaques different from non-active lesions without contrast. Conclusion: The result of this study showed that FLAIR post-inject had the highest sensitivity in detection of active MS lesions due to the CSF signal suppression in FLAIR, thus offering enough TR time recovery in active enhanced plaques.کلیدواژه ها
Multiple Sclerosis, MRI, FLAIR, Contrast mediaاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.