Detection of cryoglobulins in serum of Caspian miniature horse
- سال انتشار: 1391
- محل انتشار: مجله آرشیو رازی، دوره: 67، شماره: 1
- کد COI اختصاصی: JR_ARCHRAZI-67-1_008
- زبان مقاله: انگلیسی
- تعداد مشاهده: 79
نویسندگان
چکیده
Blood samples were collected from ۲۰ healthy miniature Caspian horses at ۳۷ °C. Isolation of cryoglobulin was performed based on a standard method in present study. Harvested sera were kept at ۴ °C for two hours and then examined for cryoglubolin. Four serum samples containing precipitate Suspicious of containing cryoglobulin were selected. Subsequently serum protein electrophoresis was performed on normal serum samples and also on four serum samples containing precipitates using an automated electrophoresis system on cellulose acetate strips. In addition Ig isotypes detection (IgG, IgM and IgA) was performed on both precipitates and serum containing precipitates using single radio immunediffusion method (SRID). A narrow-based peak on gamma region of precipitate acetate cellulose strips was observed. Precipitate concentrations were strikingly higher than normal concentration of serum immuneglobulins. It can be suggested that cryoglobulin concentration in a proportion of Caspian miniature horse is higher than other equides may be in relation with animal susceptibility to neoplasias such as lymphoma and leukemia.کلیدواژه ها
Caspian miniature horse, cryoglobulin, Serum, electrophoresisاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.