Hamidreza Alizadeh Otaghvar - Associated Professor, Department of Plastic Surgery, Iran University of Medical Sciences, Tehran, Iran
Kobra Afsordeh - Assistant Professor, Department of Anatomy, Tonekabon Azad University, Tonekabon, Iran
Mostafa Hosseini - Associated Professor, Department of General Surgery, Iran University of Medical Sciences, Tehran, Iran
Najva Mazhari - General Physician, Iran University of Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
Masoud Dousti - Resident of Department of General Surgery, Iran University of Medical Sciences, Tehran, Iran

Introduction: Wound dehiscence is one of the serious complications of surgery that is associated with mortality and morbidity (about ۴۵%); moreover, it increases medical costs. The present study assessed the incidence and predictors of wound dehiscence in trauma patients referred to Hazrat Rasool Akram Hospital. Methods: This cross-sectional study was conducted on all trauma patients with penetrating or non-penetrating abdominal wounds referred to Hazrat Rasool Akram Hospital within April ۲۰۱۷-March ۲۰۲۰. Patients were evaluated in two stages, three days after the surgery and one month later. The data were analyzed in SPSS software (version ۱۹) using Fisher's exact tests, independent t-test, Pearson's correlation coefficient, and chi-square test. A p-value less than ۰.۰۵ was considered statistically significant. Results: The present study included ۱۵۴ patients with a mean age of ۴۳.۵۳±۱۶.۸۱(age range:۱۶-۹۱ years). Moreover, the majority of the cases were female (n=۸۶; ۵۵.۸%). The wound of ۲۰ (۱۳%) patients did not heal. There was a significant relationship between male gender and wound dehiscence (P=۰.۰۱۳). The two groups did not differ in age, smoking, alcohol or opioid use, and the type of surgery. Nevertheless, wound dehiscence was significantly correlated with chemotherapy and the number of sessions. The number of hospitalization days was significantly higher in the group with wound dehiscence (P=۰.۰۰۱). Furthermore, wound dehiscence was closely correlated with low albumin, low hemoglobin, low hematocrit (leading to anemia), and high bilirubin (leading to jaundice).  Conclusions: As evidenced by the obtained results, wound dehiscence was significantly correlated with gender, low albumin, low hemoglobin, low hematocrit, bilirubin elevation, steroid usage, and chemotherapy history.

Penetrating Wound, Surgical Wound Dehiscence, Wound Healing