Shirin Rajabi - Department of Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
Farshad Rajabi - Laparoscopy Research Center, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Sarvenaz Farhangdoost - Laparoscopy Research Center, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Neda Haghighat - Laparoscopy Research Center, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Seyed Hesamaddin Banihashemi - Department of Surgery, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Background: Diet and nutrition are strongly implicated in the etiology of type ۲ diabetes. This study has investigated whether low vitamin C and β-carotene intakes were associated with glycemic control in diabetic patients.Methods: In a cross-sectional analysis of diabetic adult patients participating in Fasa Cohort Study, a ۲۴-h dietary recall was used to assess intake of fruits, vegetables, vitamin C and β-carotene. The associations between vitamin C and β-carotene intakes and glycemic control were determined in ۳ groups of normal glucose tolerance, pre-diabetes mellitus, and type ۲ diabetes mellitus (T۲DM) and the relationship between fasting blood glucose (FBS) and vitamin C and β-carotene intakes wasinvestigated.Results: There were no differences between groups for intake of total vitamin C and β-carotene (p>۰.۰۵). An inverse relation was recognized between intake of total vitamin C and β-carotene and FBS (p<۰.۰۵).Conclusion: A negative association was observed between FBS and intake of vitamin C and β-carotene; however more experimental studies are needed to establish whether increase in intake of vitamin C and β-carotene can improve FBS level and prevent T۲DM.

Vitamin C, β-carotene, Fasting blood glucose, Type ۲ diabetes mellitus, Fasa Cohort Study