Evaluation of the effects and side effects of pyrrolizidine alkaloids in medicinal plants
سال انتشار: 1398
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 116
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شناسه ملی سند علمی:
JR_TBSRJ-1-4_002
تاریخ نمایه سازی: 11 آذر 1402
چکیده مقاله:
Medicinal plants are rich in secondary metabolites, the most important of which are alkaloids. Alkaloids are organic compounds that have diverse structural and physiological activity. Pyrrolizidine alkaloids are non-polar compounds that have side effects and harmful effects especially hepatotoxicity in addition to its medicinal properties. Therefore, due to the presence of these materials in some medicinal plants and the importance of these materials and consumption of plants, and monitoring and more precision in these cases, this study was carried out. In this paper, the information have been collected from electronic library resources and from reputable sites such as Google Scholar and Scopus, PubMed, ISI (Web of Science), and the related keywords, which was the benchmark for the period between ۱۹۹۱ and ۲۰۱۹, and about ۹۰ articles and non-electronic resources for pyrolyzidine alkaloids, Medicinal plants, their effects, and their experiences and experiences were evaluated. Pyrrolizidine alkoxides in some dark Vegetable plants such as Leguminosae, Asteraceae, Orchidoceae, Boraginaceae family have been reported. Consumption of herbal products has been commonplace from centuries ago and is vital importance in various parts of the world, today. Many alkaloids are mutagenic and carcinogenic to humans. PAS-containing plants are present in most parts of the world and cause poisoning and damage to humans, livestock and wildlife.Pyrrolizidine alkaloids, which are found in some plants, can be harmed to body tissues, important properties and medicinal effects, of course, have also been reported, which requires it to be used for studying, knowing and recognizing the structure, organs and plants.
کلیدواژه ها:
نویسندگان
hamed fathi
Pharmaceutical Science Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran
Mohammad Azadbakht
The Health of Plant and Livestock Products Research Center, Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
Niusha Esmaealzadeh
Department of Persian medicine, school of pharmacy, Tehran University of Medical Science, Tehran, Iran
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