In vitro antifungal properties of Pistacia atlantica and olive extracts on different fungal species

  • سال انتشار: 1394
  • محل انتشار: مجله قارچ شناسی پزشکی، دوره: 1، شماره: 4
  • کد COI اختصاصی: JR_CUMM-1-4_008
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 67
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نویسندگان

Zahra Shialy

Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Majid Zarrin

Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Batool Sadeghi-Nejad

Abadan School of Medical Sciences, Abadan, Iran and Cellular, Molecular Research Center of Ahvaz Jundishapur University of Medical Sciences, Ahwaz, Iran

S Yusef Naanaie

Agricultural and Natural Resources Research Center

چکیده

Background and Purpose: Pistacia atlantica, which belongs to the Anacardiaceae family, grows in the Zagrossian region of Iran. The aim of this study was to evaluate the antifungal properties of Pistacia atlantica and olive leaf extracts against different fungal species. Materials and Methods: In this study, we assessed the activities of olive leaf extracts and Pistacia atlantica leaf and fruit extracts against Candida species, including C. albicans, C. glabrata, C. tropicalis, and C. krusei. In addition, antifungal activities against three filamentous species, i.e., Aspergillus niger, Aspergillus flavus, and Aspergillus fumigates, were assessed, using the agar-well diffusion method. Results: The minimal inhibitory concentrations (MICs) values of fruit and leaf extracts from Pistacia atlantica ranged ۶.۲۵-۱۲.۵ mg ml-۱ and ۶.۲۵-۲۵ mg ml-۱ against the tested Candida and Aspergillus species, respectively. The olive leaf extracts showed no activity against Candida species or Aspergillus flavus, while they exhibited antifungal potency against Aspergillus niger and Aspergillus fumigatus (MIC: ۱۲.۵-۲۵ mg/ml). The MICs of the mixture of selected extracts ranged from ۶.۲۵ to ۲۵ mg/ml. Conclusion: Based on the results, the ethanolic extracts of the selected plants exhibited antifungal potency against the tested fungi and could be used as natural antifungal agents.

کلیدواژه ها

Antifungal properties, Fungi, Olive leaf, Pistacia Atlantica

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