Catastrophic Candida prosthetic valve endocarditis and COVID-۱۹ comorbidity: A rare case

  • سال انتشار: 1400
  • محل انتشار: سرطان معده، دوره: 7، شماره: 2
  • کد COI اختصاصی: JR_CUMM-7-2_008
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 55
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نویسندگان

Lotfollah davoodi

Antimicrobial Resistance Research Center, Communicable Diseases Institute, and Department of Infectious Diseases, Mazandaran University of Medical Sciences, Sari, Iran

Leila Faeli

Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Rogheye Mirzakhani

Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran

Rozita Jalalian

Department of Cardiology, Mazandaran University of Medical Sciences, Sari, Iran

Tahereh Shokohi

Invasive Fungi Research Center(IFRC),Communicable Diseases Institute, and Department of Medical Mycology, Mazandaran University of Medical Sciences, Sari, Iran.

Firoozeh Kermani

Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

چکیده

Background and Purpose: Coronavirus disease ۲۰۱۹ (COVID-۱۹) and Candida prostatic valve endocarditis present various clinical manifestations which may overlap;hence, discrimination between them is extremely difficult.Case report: The case was a ۶۶-year-old man with a past medical history of mitral and aortic valves replacement one year before COVID-۱۹ co-infection. He was admitted with fever (for ۷ days), shortness of breath, cough, seizure, lethargy,headache, and ۸۵% oxygen saturation. Transesophageal echocardiography revealed multiple large-sized, highly mobile masses on both sides of the mechanical mitral valve highly suggestive of vegetation. Chest computed tomography scanning showed simulating scattered COVID-۱۹ peripheral ground-glass opacities confirmed by reverse-transcription polymerase chain reaction. The set of blood cultures yieldedyeast colonies that were identified as Candida tropicalis. The patient died of septic shock shortly after receiving antifungal therapy.Conclusion: This case emphasized the importance of early diagnosis andimplementation of antifungal treatment, particularly in patients with prosthetic cardiacvalves, to reduce their unfavorable outcomes in COVID-۱۹ patients

کلیدواژه ها

Candida endocarditis, case report, comorbidity, COVID-۱۹, Prosthetic valve replacement, SARS-CoV-۲, TRANSESOPHAGEAL ECHOCARDIOGRAPHY

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