Martin Gnoni - Department of Internal Medicine, Good Samaritan Hospital, Cincinnati, Ohio, United States of America
Timothy McCann - Trihealth Internal Medicine, Infectious Diseases, Cincinnati, Ohio, United States of America
Adrian Riva-Moscoso - School of Medicine, Peruvian University of Applied Sciences, Lima, Peru
Fortunato Príncipe-Meneses - School of Medicine, Peruvian University of Applied Sciences, Lima, Peru
Diego Chambergo-Michilot - School of Medicine, Scientific University of the South, Lima, Peru

Background and Purpose: Histoplasma capsulatum is the cause of a prevalent fungal disease in certain regions in the United States of America, like Ohio and the Mississippi River. Its clinical manifestations range from asymptomatic to life-threatening diseases,according to the immune system. A definitive diagnosis is made by biopsy.Case report: Two middle-aged brothers presented with a nine-day history of severe progressive dyspnea. Both were living in Cincinnati, Ohio, and encountered bird droppings ۷ days prior to symptoms while working on a roofing project. It should be mentioned that they were not wearing masks. After extensive testing, they were diagnosed with acute pulmonary histoplasmosis. Both were successfully treated with azole-derivative fungal therapy.Conclusion: This is the first case of histoplasmosis acquired through occupational exposure related to roofing and is unique given the two patients were siblings

Fungal, Histoplasmosis, Ohio, Spores, United States