The Relationship Between Serum Uric Acid and Cardiometabolic Risk Factors in Iranian Children and Adolescents
- سال انتشار: 1400
- محل انتشار: مجله پزشکی کودکان، دوره: 9، شماره: 2
- کد COI اختصاصی: JR_JPRE-9-2_011
- زبان مقاله: انگلیسی
- تعداد مشاهده: 52
نویسندگان
Department of Nutrition, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
چکیده
Context: There has been an increasing interest in epidemiological and clinical studies concerning the role of uric acid in cardiometabolic diseases, especially in children and adolescents. However, these potential relationships remain undiscovered; accordingly, its pathophysiological mechanisms remain unrecognized. This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents. Objectives: This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents. Methods: The data of ۵۹۵ individuals aged ۷-۱۸ years were assessed in this research. Anthropometric measurements and laboratory tests were performed according to standardized protocols. Results: The Mean±SD age of the ۵۹۵ explored students was ۱۲.۳۹±۳.۰۷ years. The overall Mean±SD SUA level of the study participants was measured as ۴.۲۲±۱.۱۳ mg/dL, with significant gender-wise differences (۴.۰۴±۰.۹۷ mg/dL vs ۴.۳۸±۱.۲۴ mg/dL, respectively; P< ۰.۰۵). The prevalence of hyperuricemia based on the ۹۰th percentile of SUA levels was equal to ۱۰.۶%. There was a positive association between SUA levels and abdominal obesity (waist circumference: ≥۹۰th percentile) [Odds Ratio (OR): ۱.۵۴; ۹۵% Confidence Interval (CI): ۱.۲۶ to ۱.۸۶] and general obesity [gender-specific Body Mass Index (BMI) for > ۹۵th percentile] (OR: ۲.۳۲; ۹۵% CI: ۱.۷۴ to ۳.۱۱). Conclusions: This study suggested BMI and waist circumference as cardiometabolic risk factors, i.e. significantly associated with SUA levels in children and adolescents.کلیدواژه ها
Uric acid, Metabolic syndrome, Obesity, Risk factorsاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.