Rabies Virus Infection: A Case Series and Literature Review

  • سال انتشار: 1401
  • محل انتشار: مجله پزشکی کودکان، دوره: 10، شماره: 4
  • کد COI اختصاصی: JR_JPRE-10-4_006
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 218
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نویسندگان

Shiva Shadani

Department of Pediatrics, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.

Fahimeh Ghasemi

Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Mahsa Kamali

Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Mohammad Reza Navaeifar

Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Ahmad Alikhani

Department of Infectious Diseases, Antimicrobial Resistance Research Center and Communicable Disease Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Shahriar Alian

Department of Infectious Diseases, Antimicrobial Resistance Research Center and Communicable Disease Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Alireza Davoudi Badabi

Department of Infectious Diseases, Antimicrobial Resistance Research Center and Communicable Disease Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Mohammad Sadegh Rezai

Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.

چکیده

Background: Rabies is a fatal and often neglected disease leading to encephalomyelitis following a bite by an infected mammal. According to the necessity of rabies disease in Iran, we present four cases of rabies virus infection.  Case Presentation: We presented ۴ cases of rabies virus infection hospitalized in different hospitals in Iran in ۲۰۲۱-۲۰۲۲. Three patients were male. The youngest patient was ۶ years old and the oldest was ۸۱ years old. In all ۴ cases, RT-PCR detected the positive virus infection. Three cases received rabies immunoglobulin. All of them received at least one dose of rabies vaccination; but, unfortunately, all patients died. Conclusion: The present case series showed the necessity of early rabies vaccination and also the early organization of stray dogs in the community. Unfortunately, two cases were lost to follow-up. So, the population education and follow-up of suspected rabies patients must be taken seriously by healthcare facilities.

کلیدواژه ها

Rabies virus, Hydrophobia, RT-PCR, Vaccination

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