Masoud Golpour - Department of Dermatology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IR Iran
Javad Ghaffari - Infectious Disease Research Center with Focus on Nosocomial Infection, Bou-Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, IR Iran
Abbas Dabbaghzadeh - Infectious Disease Research Center with Focus on Nosocomial Infection, Bou-Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, IR Iran
Javad Rezaiefard - Faculty of Medicine, Mazandaran University of Medical sciences, Sari, Iran

Context: Atopic dermatitis is a chronic, relapsing skin disorder that affects all ages including infancy and childhood. There are many proved and unproved treatments for atopic dermatitis. Evidence Acquisition: Data sources of this narrative review included studies about pediatric atopic dermatitis with the following keywords, pediatric, atopic dermatitis, immunity, acute, chronic, pruritic inflammatory skin disorder, infancy, childhood, diagnosis, management and treatment. All of the articles were written in English language with full text on management or treatment. Results: Innate and adaptive immune system involved atopic dermatitis. Major characteristics of atopic dermatitis include pruritus, chronic or relapsing lesions and personal or family history of atopic disease. There is no specific treatment for atopic dermatitis. The treatment included rehydration, emollients, topical steroid, calcineurin inhibitors and immunosuppressant. Crisaborole topical ointment, a PDE۴ anti-inflammatory topical agent (phase three of the research) could be effective in atopic dermatitis. Conclusions: Avoidance from trigger factors and emollients are basic treatments of atopic dermatitis.

Pediatrics, Dermatitis, Atopic, Theapy