Photodegradation of the Antibiotic Penicillin G in the Aqueous Solution using UV-A Radiation
- سال انتشار: 1392
- محل انتشار: مجله علوم پزشکی ایران، دوره: 1، شماره: 3
- کد COI اختصاصی: JR_JHES-1-3_006
- زبان مقاله: انگلیسی
- تعداد مشاهده: 146
نویسندگان
Department of Environmental Health Engineering, School of Health
Department of Environmental Health Engineering, School of Health
Department of Environmental Health Engineering, School of Health
چکیده
Background and purpose: Highly consumption of antibiotics and their entrance into the environment has increased concerns all over the world. These compounds enter to the environment through an incomplete metabolism and a considerable amount of them cannot be removed using usual waste filtration systems. Therefore, the present study aimed to investigate the feasibility of using ultraviolet radiation (UV-A) to remove penicillin G (PENG) from aqueous phase and determining its removal efficiency. Materials and Methods: The experiments were carried out in the batch mode. The samples were assessed in a ۲-liter reactor. In order to investigate the effect of UV-A radiation on the removal rate of antibiotic penicillin G (PENG), the following parameters were studied. Three concentration levels of PENG antibiotic (۱۰,۲۵,and ۴۵ mg/l) were exposed to UV-A at three pH levels (۳,۷,۱۱) and were evaluated at four reaction times (۳۰,۶۰,۹۰, and ۱۲۰ min). Antibiotic penicillin G (PENG) was determined using HPLC instrument (Waters YL۹۱۰۰,USA) and results analyzed using factorial design software. Results: The finding demonstrated that antibiotic removal rate increased by decreasing pH and decreasing the initial concentration of antibiotic and increasing contact time. The maximum rate of penicillin G removal occurred in acidic pH (pH=۳) is as much as ۳۸%. All of the variables in the process have been statistically significant effect (p< ۰.۰۰۱). Conclusion: Results showed that by reducing the pH, increasing contact time and reducing the antibiotic concentration, the removal rate increases. In conclusion, photodegradation process using UV-A may enhance the rate of penicillin G degradation in polluted water and could be used as a complementary step for other chemical and biological processes to remove penicillin G from the aqueous solution. Therefore, UV-A process in conjugate with the other processes is an appropriate method for reducing antibiotic penicillin G in polluted water resources.کلیدواژه ها
Antibiotic, Penicillin G, UV-A Radiation, Photodegradation, Removal, Aqueous Solutionاطلاعات بیشتر در مورد COI
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