Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran
- سال انتشار: 1399
- محل انتشار: مجله گیاهان دارویی و محصولات فرعی، دوره: 9، شماره: 0
- کد COI اختصاصی: JR_JJMPB-9-0_013
- زبان مقاله: انگلیسی
- تعداد مشاهده: 100
نویسندگان
Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
Department of Chemical Engineering, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
Cellular and Molecular Biology Research Center, Babol University of Medical Sciences, Babol, Iran
چکیده
Medicinal plants can be used in food, pharmaceutical and cosmetic products due to their biological and nutritional properties. The objective of this research was to examine the chemical composition, antimicrobial and analgesic activity of Rosmarinus officinalis L. plant originating Amol, north of Iran for the first time. The essential oil was obtained by hydrodistillation. Gas chromatography-mass spectrometry study was used for oil analysis. Staphylococcus aureus, Escherichia coli, Salmonella enteritidis, Bacillus subtilis and Candida albicans were used to examine the antimicrobial activity of the essential oils using agar disk diffusion assay. GC-MS analysis revealed that the oil was dominated by ۱,۸-cineole (۲۰.۲۰%), α-Pinene (۱۷.۲۹%) and borneol (۷.۵۹%). Antimicrobial assays of different dilutions of essential oil showed significant antimicrobial activity against gram-positive bacteria. Furthermore, the water and ethanolic extracts prevented the pain resulting from hot-plate test. The results suggested Rosmarinus officinalis from Amol as an alternative natural compound which has antimicrobial and analgesic effects to use in pharmaceutical industries.کلیدواژه ها
analgesic, Antimicrobial activity, chemical composition, essential oil, Extract, Rosmarinus officinalisاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.