بررسی تاثیر مکمل یاری با ویتامین C تزریقی بر میزان خستگی بیماران همودیالیزی

سال انتشار: 1392
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 68

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شناسه ملی سند علمی:

JR_JCCNUR-6-3_001

تاریخ نمایه سازی: 29 آبان 1402

چکیده مقاله:

Aims : Fatigue is one of the most common dialysis side effects and it has been among the main nursing diagnosis in hemodialysis patients and it can predict cardiovascular events and its mortality in hemodialysis patients as a bioalarm. Considering that decrease in Serum level of vitamin C is one of the main causes of fatigue in these patients, this study had been done with the aim of evaluating the effect of supplementation with intravenous vitamin C on fatigue in hemodialysis patients . Methods : In a randomized, parallel group, double-blind clinical trial , ۱۷۷ patients with chronic renal failure who referred to hemodialysis units of Baqiatallah and Chamran hospital in Tehran were studied. They distributed in three groups of experimental, control and placebo in ۲۰۱۱. In addition to demographic questionnaire , multidimensional questionnaire (MFI) had also been used for determining fatigue before and after intervention. Then in experimental group an ۲.۵cc injection contacting ۲۵۰ mg vitamin C was injected three times every week, at the end of each dialysis session via the intravenous route , for ۸ weeks. In the placebo group normal saline placebo had been injected with the same amount for the same time and there was no intervention in the control group. In order to analyze data statistically and compare them between groups, SPSS statistical software , and Chi square, T-test, Paired t-test and ANOVA were used . Results: Complain of fatigue was observed in ۸۱/۶ % of patients and ۳۰/۷% of these patients suffered from severe fatigue before the intervention . The average loss of activity, physical fatigue and general fatigue had respectively higher mean in compare with the other five of fatigue dimensions .The mean of total scores of fatigue five dimensions was ۶۵.۳۹±۱۵.۹۲. After the end of intervention there was significant difference between findings of the three groups fatigue mean was decreased in experimental group to ( ۵۲.۲۸±۱۳.۸۲). Conclusion: Vitamin C supplementation can decrease fatigue significantly and it can be used as a simple, safe and inexpensive way .

کلیدواژه ها:

خستگی ، نارسایی مزمن کلیوی ، همودیالیز ، مکمل یاری ویتامین C