Comparison of ۵-year Incidence of Type ۲ Diabetes in Obese and Non-Obese Adult Population: The YaHs Cohort
- سال انتشار: 1402
- محل انتشار: فصلنامه تغذیه و امنیت غذایی، دوره: 8، شماره: 4
- کد COI اختصاصی: JR_JNFS-8-4_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 58
نویسندگان
Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Yazd Cardiovascular Research Center, Non-communicable diseases research institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Internal Medicine, BH۱۰-۶۴۲, Rue du Bugnon ۴۶, CH-۱۰۱۱ Lausanne, Switzerland
Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Health Sciences, Bielefeld University, Bielefeld, Germany
Mohammadtaghi Sarebanhassanabadi
Yazd Cardiovascular Research Center, Non-communicable diseases research institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
چکیده
Background: Obesity is an important predictor of diabetes. Defining the risk of diabetes among obese subjects is important for preventive health strategies. This study aims to compare the ۵-year incidence of diabetes in obese and non-obese adult participants aged ۲۰-۷۰ years in a large population sample of central Iran. Methods: In this prospective study, ۹۹۶۴ people aged ۲۰-۷۰ years were selected between ۲۰۱۴ and ۲۰۱۵ using multi-stage cluster sampling from Yazd Greater Area, Iran. Participants with diabetes were excluded and non-diabetic individuals were evaluated for incident diabetes after a five-year follow-up. Logistic regression was used to find the association between obesity and ۵-year incidence of diabetes in bivariate, and multivariate adjusted models for age, sex, physical activity, medical history, marital status, smoking, and education. Results: Out of the initial ۹۹۶۴ participants, ۱۳۸۳ (۱۴%) were excluded due to prevalence of diabetes. The remaining ۸۴۱۳ (۸۶.۰%) participants were re-examined in ۲۰۱۹-۲۰۲۰. After five years of follow up, diabetes occurred in ۶.۶% (n=۵۵۶) of the participants. The incidence of diabetes in obese men and women was ۱۰.۴% (n=۱۰۹) and ۹.۹% (n=۲۶۴), respectively; however, it was ۴.۵% (n=۱۴۳) and ۲.۸% (n=۴۰) in their non-obese counterparts (P< ۰.۰۱). After multivariate analysis, obesity was associated with a higher likelihood of diabetes in men (OR=۱.۷۷, ۹۵% CI: ۱.۳۳-۲.۳۵), women (OR=۲.۲۳, ۹۵% CI: ۱.۵۵-۳.۲۱), and overall (OR=۱.۹۹, ۹۵%CI: ۱.۶۰-۲.۴۸). Similar findings were obtained in participants aged under and over ۶۰ years (P< ۰.۰۵). Conclusion: There was a positive association between obesity and ۵-year incidence of diabetes in an Iranian adult population. Interventions are required to change lifestyle in the adult population especially in younger participants to prevent obesity and diabetes. Corresponding Author:Mohammadtaghi Sarebanhassanabadi View Orcid in Profile You can search for this author in PubMed Google Scholar Profileکلیدواژه ها
Diabetes, Obesity, Incidence, Cohort studyاطلاعات بیشتر در مورد COI
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