Effect of Concurrent Resistance-Aerobic Training on Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Pediatric Type ۱ Diabetes: A Randomized Trial
- سال انتشار: 1401
- محل انتشار: مجله دیابت و چاقی ایران، دوره: 15، شماره: 1
- کد COI اختصاصی: JR_IJDO-15-1_007
- زبان مقاله: انگلیسی
- تعداد مشاهده: 60
نویسندگان
Ph.D Candidate of Exercise Physiology, Faculty of Humanities, Rasht Branch, Islamic Azad University, Rasht, Iran.
Department of Exercise Physiology, Faculty of Humanities, Rasht Branch, Islamic Azad University, Rasht, Iran.
Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
چکیده
Objective: The role of post-exercise on the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) is not evident in pediatrics with type ۱ diabetes (T۱D) yet. This paper reports the results of a research study on how concurrent exercise training affects NLR and PLR in children with T۱D. Materials and Methods: In this randomized controlled trial, ۴۰ children (boys and girls aged ۱۱.۱۱ ±۲.۲۹ years) were randomly divided into an experimental (n=۲۰) and a control group (n=۲۰). The training program included concurrent resistance-aerobic training, which was intermittently performed for ۶۰ minutes at a rate of three times a week for ۱۶ weeks. The participants were analyzed for blood glucose homeostasis, NLR and PLR before and after the program. Data were analyzed by SPSS ۲۲ software with paired T-test and covariance analysis (P< ۰.۰۵). Results: The results showed that PLR significantly (P= ۰.۰۰۲) decreased in the exercise group after ۱۶ weeks of concurrent training. This significance was observed between the groups too (P= ۰.۰۰۳). HbA۱c decreased both in the exercise group and between the groups (P= ۰.۰۰۱, P= ۰.۰۰۳). NLR exhibited a significant increase both in the exercise group (P= ۰.۰۲۱( and between the groups )P= ۰.۰۱۲(. Conclusion: Concurrent exercise training reduces PLR and HbA۱c in children with T۱D, which may be related to the anti-inflammatory effects of exercise training.کلیدواژه ها
Diabetes mellitus, Neutrophil- lymphocyte ratio, Platelet-lymphocyte ratio, Pediatricاطلاعات بیشتر در مورد COI
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